Background: Neuromyelitis optica (NMO) is a neurological disease characterized by optic neuritis and transverse myelitis with long spinal cord lesion. Recently, NMO-IgG, which recognizes the aquaporin-4 (AQP-4), was identified in sera from patients with NMO. AQP-4 is a water channel expressed in astrocytes and ependymal cells throughout the brain and spinal cord
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- About NMO
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- NMO FAQsAnswers to some of the most frequently asked questions about NMO, featuring video interviews with leading scientists.
- NMO & Multiple Sclerosis: Did You Know?MS and NMO are treated in different ways and early detection and treatment help ensure best outcomes.
- DiagnosisThe release of new diagnostic criteria for NMO by the International Panel for Neuromyelitis Optica Diagnosis (IPND).
- Recommended ReadingSuggested resources to read from past NMO Patient Day conferences.
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- Approved TherapeuticsAfter more than 100 years with no approved treatment, today there are three approved therapeutics for NMOSD.
- Clinical Trials in NMOFind access to information, FAQs, and video resources about ongoing clinical trials in Neuromyelitis Optica Spectrum Disorder.
- ResearchBrowse through the results of over $70 million donated to basic and clinical research to solve neuromyelitis optica.
- NMOSD and COVID-19With information changing on a daily basis, we are reaching out to the NMOSD community to aid in your navigation of the many questions at hand.
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- About Us
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- Foundation EventsCalendar of past and upcoming foundation events, including NMO Roundtable Conference and NMO Patient Days.
- Special ProjectsLearn more about special projects including the ICC, IPND, and the CIRCLES Biorepository.
- CIRCLESCIRCLES is a clinical research study that focuses on better understanding and enabling cures for NMO.
- Industry CouncilThe Guthy-Jackson Charitable Foundation invites all members of industry to join our industry council.
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- International Clinical ConsortiumThe ICC consists of thought leaders from over 25 countries performing translational research and medicine focused on NMO.
- Medical Advisors and ConsultantsThe medical advisors and consultants to The Guthy-Jackson Charitable Foundation include experts from UCLA, Johns Hopkins, and more.
- PressStay up to date with featured press regarding NMO and The Guthy-Jackson Charitable Foundation.
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- Newly Diagnosed
- Breakthroughs
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- Predict | Clinical BiomarkersThe exciting science of biomarkers and big data analysis is enabling GJCF and its research partners to predict risks, relapses and personalized therapy.
- Protect | Against RelapsesApproved medicines offer a best chance to minimize relapse risks. Now GJCF is driving new treatments to stop relapses in their tracks if they do occur.
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- Pioneer | Curative TherapiesApproved therapies are a great first step toward preventing relapses. GJCF is now pioneering bold new approaches to cure NMOSD once and for all.
- Promote | Advocacy for AllPatients, caregivers and loved ones are best served with credible information and healthcare access. GJCF promotes wellness via education and advocacy.
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- Advocacy
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- EventsNMO events are happening all around the world. Browse our listing of advocacy events, educational seminars, and more. Or post your own!
- Patient Advocacy CouncilThe NMO Patient Advocacy Council provides educational resources, extends awareness to urban and rural communities, and connects patients, caregivers, and families in the NMO community.
- NMOStoriesNMOStories exists to provide everyone with a voice, every stakeholder for NMO from patients and caregivers to clinicians and nurses.
- PoliticsLearn more about how to get engaged with NMOSD political advocacy.
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- Support GroupsNo matter where you are on your NMO journey or how NMO affects your life, support groups aim to offer a sense of comfort and community.
- ContactContact The Guthy-Jackson Charitable Foundation with questions about NMO, advocacy, clinical trials, support, donations, and more.
- BlogBrowse the NMOtion Blog to get the latest information regarding NMO research and advocacy, including Q&As with top researchers.
- My AccountLog in to post events, create donation pages, and get involved in the NMO community.
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- Research
- Resources
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- 10 Steps Forward10 Steps Forward that may be useful for those newly diagnosed with NMOSD or MOGAD
- NMO Patient Resource GuideOur full-text NMO Patient Resource Guide offers help and information to those who have been affected by NMO.
- VideosExplore our massive library of videos, examining everything from patient care, research, and the work of the foundation.
- Tools for DownloadDownload resources including the NMO Patient Guide, NMO/MS Brochure, Fact Sheets, and more.
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- Podcasts and WebinarsListen to podcasts and webinars from the foundation along with our industry and nonprofit partners in the rare disease community.
- Spectrum LibraryBrowse over 1000 research publications related to neuromyelitis optica, including some of the groundbreaking research sponsored by the foundation.
- Connect the DocsExplore our map with locations of over 350 international clinicians who are experts in diagnosing and treating NMO.
- SearchSearch our website for pages, groups, resources, articles, videos, and more.
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- Patient Stories
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