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About NMO
About NMO
Neuromyelitis optica (NMO) and neuromyelitis optica spectrum disorder (NMOSD) occur when the immune system mistakes normal tissues of the central nervous system as being foreign.
10 Steps Forward
10 Steps Forward that may be useful for those newly diagnosed with NMOSD or MOGAD
NMO FAQs
Answers to some of the most frequently asked questions about NMO, featuring video interviews with leading scientists.
NMO & Multiple Sclerosis: Did You Know?
MS and NMO are treated in different ways and early detection and treatment help ensure best outcomes.
Approved Therapeutics
After more than 100 years with no approved treatment, today there are four approved therapeutics for NMOSD.
Library
Suggested resources to read from past NMO Patient Day conferences.
Diagnosis
The release of new diagnostic criteria for NMO by the International Panel for Neuromyelitis Optica Diagnosis (IPND).
About Us
About Us
The Guthy-Jackson Charitable Foundation was established in 2008 when our beautiful teenage daughter was first diagnosed with Neuromyelitis Optica (NMO), a life-threatening autoimmune disease.
Foundation Events
Calendar of past and upcoming foundation events, including NMO Roundtable Conference and NMO Patient Days.
CIRCLES
CIRCLES is a clinical research study that focuses on better understanding and enabling cures for NMO.
Industry Council
The Guthy-Jackson Charitable Foundation invites all members of industry to join our industry council.
International Clinical Consortium
The ICC consists of thought leaders from over 25 countries performing translational research and medicine focused on NMO.
Medical Advisors
The medical advisors and consultants to The Guthy-Jackson Charitable Foundation include experts from UCLA, Johns Hopkins, and more.
Press
Stay up to date with featured press regarding NMO and The Guthy-Jackson Charitable Foundation.
Breakthroughs
Breakthroughs & Beyond – Priorities
In pioneering a new model of collaboration, GJCF began with a mission critical goal to fund research that accelerates development and approval of safe and effective therapies for NMOSD.
Pioneer | Curative Therapies
Approved therapies are a great first step toward preventing relapses. GJCF is now pioneering bold new approaches to cure NMOSD once and for all.
Predict | Clinical Biomarkers
The exciting science of biomarkers and big data analysis is enabling GJCF and its research partners to predict risks, relapses and personalized therapy.
Protect | Against Relapses
Approved medicines offer a best chance to minimize relapse risks. Now GJCF is driving new treatments to stop relapses in their tracks if they do occur.
Education
Research
Resources
NMO Resources
NMO Resources. The Guthy-Jackson Charitable Foundation is pleased to bring you this app full of resources relating to NMO.
New to NMO
We are here to help you navigate your journey and provide current resources and educational information that will empower you to advocate for yourself and your loved one.
NMO Patient Resource Guide
Our full-text NMO Patient Resource Guide offers help and information to those who have been affected by NMO.
Discover Advocates
Explore advocacy groups and resources committed to empowering patients and families through every step of their rare disease journey.
Connect the Docs
Explore our map with locations of over 350 international clinicians who are experts in diagnosing and treating NMO.
Videos
Explore our massive library of videos, examining everything from patient care, research, and the work of the foundation.
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Video Library
Cures through Collaboration: Funding a Team Approach to Disease Research
Watch “Los Angeles NMO Patient Day 2025” on YouTube
Neuromyelitis Optica: Behind the Mystery of NMO
GJCF 15th Anniversary
Ali Guthy and The Guthy-Jackson Charitable Foundation
The NMO Story
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