- 1. Advanced from the 2006 NMO Diagnostic Criteria
- 2. Authored by the International Panel on Neuromyelitis Optica Diagnosis (IPND)
- 3. Sponsored by The Guthy – Jackson Charitable Foundation
What are diagnostic criteria?
Who uses diagnostic criteria and how?
Who developed the new diagnostic criteria, how long did it take, and what was the process?
Describe the process by which these new criteria will be evaluated / validated in the clinic.
Why did the diagnostic criteria from 2006 need to be updated?
Summarize the current understanding of the difference between NMO and NMOSD and how their diagnostic criteria differ.
Do the 2015 criteria set a higher standard for diagnosing NMO or NMOSD around the world?
As a result of these new criteria, do you think the incidence / prevalence of NMO around the world will increase, decrease, or stay the same?
Is the official term for Neuromyelitis Optica (NMO) now Neuromyelitis Optica Spectrum Disorder (NMOSD)? If so, why?
Many people still refer to NMO as “Devic’s Disease.” Should we stop using the term “Devic’s Disease” and only use NMO or NMOSD? If so, why?
How will these new criteria impact current and future NMO patients?
How are the new diagnostic criteria most likely to benefit patients (e.g. more rapid diagnoses, more accurate diagnoses, etc.)?
How might the new diagnostic criteria impact NMOSD clinical trials or clinical studies?
Athena Diagnostics, Inc.
Assay Method: ELISA** Detects anti-AQP4 antibody
Test Code: 193
Turn-Around Time: 5 – 7 days
Estimated Cost: $840 – Insurance; $560 – Hospital or reference laboratory
Assay Method: Outsourced to Quest Diagnostics
Test Code: Members must inquire
Turn-Around Time: Members must inquire
Estimated Cost: Members must inquire
Assay Method: Cell binding Assay (CBA) / Detects IgG Specific for AQP4 by Fluorescence-Activated Cell Sorting (FACS)
NMOFS: Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Serum
NMOFC: Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Spinal Fluid
Turn-Around Time: 4 – 7 days
Estimated Cost: Based on client pricing. Institutional billing only