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About NMO
About NMO
Neuromyelitis optica (NMO) and neuromyelitis optica spectrum disorder (NMOSD) occur when the immune system mistakes normal tissues of the central nervous system as being foreign.
NMO FAQs
Answers to some of the most frequently asked questions about NMO, featuring video interviews with leading scientists.
NMO & Multiple Sclerosis: Did You Know?
MS and NMO are treated in different ways and early detection and treatment help ensure best outcomes.
Diagnosis
The release of new diagnostic criteria for NMO by the International Panel for Neuromyelitis Optica Diagnosis (IPND).
Recommended Reading
Suggested resources to read from past NMO Patient Day conferences.
Approved Therapeutics
After more than 100 years with no approved treatment, today there are three approved therapeutics for NMOSD.
Clinical Trials in NMO
Find access to information, FAQs, and video resources about ongoing clinical trials in Neuromyelitis Optica Spectrum Disorder.
Funded Researchers
Browse through the results of over $70 million donated to basic and clinical research to solve neuromyelitis optica.
NMOSD and COVID-19
With information changing on a daily basis, we are reaching out to the NMOSD community to aid in your navigation of the many questions at hand.
About Us
About Us
The Guthy-Jackson Charitable Foundation was established in 2008 when our beautiful teenage daughter was first diagnosed with Neuromyelitis Optica (NMO), a life-threatening autoimmune disease.
Foundation Events
Calendar of past and upcoming foundation events, including NMO Roundtable Conference and NMO Patient Days.
Special Projects
Learn more about special projects including the ICC, IPND, and the CIRCLES Biorepository.
CIRCLES
CIRCLES is a clinical research study that focuses on better understanding and enabling cures for NMO.
Industry Council
The Guthy-Jackson Charitable Foundation invites all members of industry to join our industry council.
International Clinical Consortium
The ICC consists of thought leaders from over 25 countries performing translational research and medicine focused on NMO.
Medical Advisors
The medical advisors and consultants to The Guthy-Jackson Charitable Foundation include experts from UCLA, Johns Hopkins, and more.
Press
Stay up to date with featured press regarding NMO and The Guthy-Jackson Charitable Foundation.
New to NMO
Breakthroughs
Breakthroughs & Beyond – Priorities
In pioneering a new model of collaboration, GJCF began with a mission critical goal to fund research that accelerates development and approval of safe and effective therapies for NMOSD.
Predict | Clinical Biomarkers
The exciting science of biomarkers and big data analysis is enabling GJCF and its research partners to predict risks, relapses and personalized therapy.
Protect | Against Relapses
Approved medicines offer a best chance to minimize relapse risks. Now GJCF is driving new treatments to stop relapses in their tracks if they do occur.
Pioneer | Curative Therapies
Approved therapies are a great first step toward preventing relapses. GJCF is now pioneering bold new approaches to cure NMOSD once and for all.
Promote | Advocacy for All
Patients, caregivers and loved ones are best served with credible information and healthcare access. GJCF promotes wellness via education and advocacy.
Advocacy
Advocacy
A disease is not rare if it affects you, so we thank you for interest in joining the community and getting NMOtion to solve NMO!
Events
NMO events are happening all around the world. Browse our listing of advocacy events, educational seminars, and more. Or post your own!
Patient Advocacy Council
Provides educational resources, extends awareness to urban and rural communities, and connects patients, caregivers, and families in the NMO community.
Adapt-Ability
Adapt-Ability is a collaborative video series designed to improve everyday life for the NMO, MOGAD, and neuroimmune community.
NMO Helpline
A resource for individuals seeking education, support, and connections within the NMO community.
NMOStories
NMOStories exists to provide everyone with a voice, every stakeholder for NMO from patients and caregivers to clinicians and nurses.
Support Groups
No matter where you are on your NMO journey or how NMO affects your life, support groups aim to offer a sense of comfort and community.
Contact
Contact The Guthy-Jackson Charitable Foundation with questions about NMO, advocacy, clinical trials, support, donations, and more.
My Account
Log in to post events, create donation pages, and get involved in the NMO community.
Education
Research
Resources
NMO Resources
NMO Resources. The Guthy-Jackson Charitable Foundation is pleased to bring you this app full of resources relating to NMO.
10 Steps Forward
10 Steps Forward that may be useful for those newly diagnosed with NMOSD or MOGAD
NMO Patient Resource Guide
Our full-text NMO Patient Resource Guide offers help and information to those who have been affected by NMO.
Videos
Explore our massive library of videos, examining everything from patient care, research, and the work of the foundation.
Tools for Download
Download resources including the NMO Patient Guide, NMO/MS Brochure, Fact Sheets, and more.
Webinars and Breakout Sessions
Watch webinars and breakout sessions from the foundation along with our industry and nonprofit partners in the rare disease community.
Spectrum Library
Browse over 1000 research publications related to neuromyelitis optica, including some of the groundbreaking research sponsored by the foundation.
Connect the Docs
Explore our map with locations of over 350 international clinicians who are experts in diagnosing and treating NMO.
Search
Search our website for pages, groups, resources, articles, videos, and more.
NMO Helpline
A resource for individuals seeking education, support, and connections within the NMO community.
Patient Stories
Donate
Video Library
NMO Tolerization
Watch “Los Angeles NMO Patient Day 2025” on YouTube
Neuromyelitis Optica: Behind the Mystery of NMO
Artistry iNMOtion: Beyond the Science
GJCF 15th Anniversary
Ali Guthy and The Guthy-Jackson Charitable Foundation
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