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Large-Scale in-House Cell-Based Assay for Evaluating the Serostatus in Patients with Neuromyelitis Optica Spectrum Disorder Based on New Diagnostic Criteria.

Abstract BACKGROUND AND PURPOSE: The detection of aquaporin 4-IgG (AQP4-IgG) is now a critical diagnostic criterion for neuromyelitis optica spectrum disorder (NMOSD). To evaluate the serostatus of NMOSD patients based…

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Late-onset neuromyelitis optica spectrum disorder: The importance of autoantibody serostatus.

Neurol Neuroimmunol Neuroinflamm. 2019 Aug 30;6(6). pii: e607. doi: 10.1212/NXI.0000000000000607. Print 2019 Nov. Sepulveda M1, Delgado-García G1, Blanco Y1, Sola-Valls N1, Martinez-Lapiscina EH1, Armangué T1, Montejo C1, Pulido-Valdeolivas I1, Martinez-Hernandez…

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MOG-antibody associated demyelinating disease of the CNS: A clinical and pathological study in Chinese Han patients.

Abstract We aim to evaluate the clinical relevance of MOG-ab in a cohort of Chinese Han adults with CNS inflammatory demyelinating diseases (IDDs). MOG-ab and AQP4-ab were examined through a…

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Risk factors for idiopathic optic neuritis recurrence. – PubMed – NCBI

Risk factors for idiopathic optic neuritis recurrence. – PubMed – NCBI. See comment in PubMed Commons below PLoS One. 2014 Sep 25;9(9):e108580. doi: 10.1371/journal.pone.0108580. eCollection 2014. Risk factors for idiopathic…

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Serum lipoprotein levels in patients with neuromyelitis optica elevated but had little correlation with clinical presentations.

OBJECTIVE: To explore the relationship between serum lipoproteins and clinical presentations of NMO patients. To investigate the differences of serum lipoprotein levels between NMO and MS patients. PATIENTS AND METHODS:…

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A Brief Look at Some NMO FAQs

Let’s take a brief look at some of the common questions about NMO. You can read our full list of NMO FAQs here. What is NMO? NMO stands for neuromyelitis…

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Antibodies to MOG and AQP4 in adults with neuromyelitis optica and … – PubMed – NCBI

Antibodies to MOG and AQP4 in adults with neuromyelitis optica and … – PubMed – NCBI. See comment in PubMed Commons below Mult Scler. 2014 Oct 24. pii: 1352458514555785. [Epub…

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Anti-AQP(4) antibody in idiopathic acute t… [J Spinal Cord Med. 2012] – PubMed – NCBI

Anti-AQP(4) antibody in idiopathic acute t… [J Spinal Cord Med. 2012] – PubMed – NCBI. Anti-AQP(4) antibody in idiopathic acute transverse myelitis with recurrent clinical course: frequency of positivity and…

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Aquaporin 4-specific T cells in neuromyelitis opt… [Ann Neurol. 2012] – PubMed – NCBI

Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter. Varrin-Doyer M, Spencer CM, Schulze-Topphoff U, Nelson PA, Stroud RM, C Cree BA, Zamvil…

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Cerebrospinal Fluid BAFF and APRIL Levels in … [J Clin Immunol. 2012] – PubMed – NCBI

Cerebrospinal Fluid BAFF and APRIL Levels in Neuromyelitis Optica and Multiple Sclerosis Patients During Relapse. Wang H, Wang K, Zhong X, Qiu W, Dai Y, Wu A, Hu X. Source…

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Garland’s Glance: Living with NMO

By Scott Garland Since I started at the Genesee Sun, I’ve encouraged readers to suggest ideas, issues and topics you would like to see me cover. Recently, a daughter and…

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The cerebrospinal fluid immunoglobulin transcriptome and proteome i… – PubMed – NCBI

The cerebrospinal fluid immunoglobulin transcriptome and proteome i… – PubMed – NCBI. The cerebrospinal fluid immunoglobulin transcriptome and proteome in neuromyelitis optica reveals central nervous system-specific B cell populations. Kowarik…

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