mail2

Spectrum Library

ScienceDirect.com – Multiple Sclerosis and Related Disorders – Presentation of neuromyelitis optica spectrum disorder after more than twenty years of systemic sclerosis

Abstract

Neuromyelitis optica is an autoimmune disorder characterized by optic neuritis, transverse myelitis, and aquaporin-4 autoantibodies. The term “neuromyelitis optica spectrum disorder” refers neuromyelitis optica features occurring in association with other systemic rheumatologic conditions. We present a case of a 51-year-old woman with long-standing systemic sclerosis who developed transverse myelitis in association with the presence aquaporin-4 autoantibodies. This is the first report case of neuromyelitis optica spectrum disorder associated with systemic sclerosis. Given that patients with neuromyelitis optica spectrum disorder with aquaporin-4 autoantibodies have a high risk for clinical relapse, this report underscores the need for recognition of this disorder in patients with systemic sclerosis and neurological dysfunction.

Keywords
Neuromyelitis optica;
Systemic sclerosis;
Devic’s disease;
Transverse myelitis;
Aquaporin-4 antibodies;
Neuromyelitis optica spectrum disorder

Read More: ScienceDirect.com – Multiple Sclerosis and Related Disorders – Presentation of neuromyelitis optica spectrum disorder after more than twenty years of systemic sclerosis