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Spontaneous remission lasting more than a decade in untreated AQP4 antibody-positive NMOSD.

Neurol Neuroimmunol Neuroinflamm. 2017 May 2;4(4):e351. doi: 10.1212/NXI.0000000000000351. eCollection 2017 Jul.

Pandit L1, Mustafa S1

Myelin oligodendrocyte glycoprotein immunoglobulin G (anti-MOG-IgG) has been recently found to be asso- ciated with some forms of idiopathic inflammatory demyelinating CNS disorders. In a preliminary study from India, recurrent optic neuritis and isolated longitu- dinally extensive transverse myelitis were identified as the common phenotypes.1 The clinical and radiologic features of this newly discovered subset of autoimmune disorders are only beginning to be understood. In this context, we would like to draw attention to an unusual and hitherto unreported association noticed in a patient with anti-MOG-IgG–associated myelitis.