Posts tagged: function

Frederic Blanc1,2,3*, Vincent Noblet4, Barbara Jung1,3, François Rousseau4, Felix Renard2,4, Bertrand Bourre1,2, Nadine Longato1,3, Nadjette Cremel1,3, Laure Di Bitonto1,3, Catherine Kleitz1,3, Nicolas Collongues1,2, Jack Foucher5, Stephane Kremer2,6, Jean-Paul Armspach2, Jerome de Seze1,2 1 Neuropsychology Service, Department of Neurology, University Hospital of Strasbourg, Strasbourg, France, 2 LINC (Cognitive Neurosciences and Imagery Laboratory), UMR 7237, University of Strasbourg and CNRS, Strasbourg, France, 3 CMRR (Memory Resource and Research Centre), Department of Neurology, University Hospital of Strasbourg, Strasbourg, France, 4 LSIIT (Image Science, Computer Science and Remote Sensing Laboratory), UMR 7005, University of Strasbourg and CNRS, Strasbourg, France, 5 INSERM U666, University Hospital of Strasbourg, Strasbourg, France, 6 Neuroradiology service, University Hospital of Strasbourg, Strasbourg, France Abstract Top Neuromyelitis optica (NMO) is an inflammatory disease of central nervous system characterized by optic neuritis and longitudinally extensive acute transverse myelitis.

In clinical studies for the lead indication of multiple sclerosis (MS), Revimmune improves function in most patients and stops progression in over 90% of cases refractory to standard therapies.

Color coded map of spinal cord at resource.? Below is a list of cord segments and associated functions. ? Segmental Spinal Cord Level and Function ? ? Level Function ? ? Cl-C6 Neck flexors Cl-T1 Neck extensors C3, C4, C5 Supply diaphragm C5, C6 Shoulder movement, raise arm (deltoid); flexion of elbow (biceps); C6 ?externally rotates the arm (supinates) C6, C7, C8 Extends elbow and wrist (triceps and wrist extensors); pronates wrist C7, C8, Tl Flexes wrist C8, Tl Supply small muscles of the hand Tl -T6 lntercostals and trunk above the waist T7-Ll Abdominal muscles Ll, L2, L3, L4 Thigh flexion L2, L3, L4 Thigh adduction L4, L5, S1 Thigh abduction L5, S1 S2 Extension of leg at the hip (gluteus maximus) L2, L3, L4 Extension of leg at the knee (quadriceps femoris) L4, L5, S1, S2 Flexion of leg at the knee (hamstrings) L4, L5, S1 Dorsiflexion of foot (tibialis anterior) L4, L5, S1 Extension of toes L5, S1, S2 Plantar flexion of foot L5, S1, S2 Nexion of toes ? ? ?

Research Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders Klaus Lehmann-Horn , Eva Schleich , Deetje Hertzenberg , Alexander Hapfelmeier , Tania Kuempfel , Nikolas von Bubnoff , Reinhard Hohlfeld , Achim Berthele , Bernhard Hemmer and Martin S Weber ? For all author emails, please log on . Journal of Neuroinflammation 2011, 8 :146? doi:10.1186/1742-2094-8-146 Published: 26 October 2011 Abstract (provisional) Background Clinical trials evaluating anti-CD20-mediated B-cell depletion in multiple sclerosis (MS) and neuromyelitis optica (NMO) generated encouraging results.

? NARCOMS Report-2007 Registry Update Optic Neuritis in Multiple Sclerosis ? Neuromyelitis Optica Dean M. Wingerchuk, MD, MSc, FRCP(C) A Historical Perspective on NMO Neuromyelitis optica (NMO), also known as Devic’s disease, was identified more than one hundred years ago as a severe disorder affecting the spinal cord (causing paralysis) and both optic nerves (causing blindness).

The central nervous system ( CNS ) represents the largest part of the nervous system , including the brain and the spinal cord . Together with the peripheral nervous system , it has a fundamental role in the control of behavior

With a concentration of 55,000 mM, water is by far the most prevalent molecule in biological systems.

Neuromyelitis optica (NMO) is an inflammatory autoimmune demyelinating disease of the central nervous system (CNS) which in autoantibodies produced by patients with NMO (NMO-IgG) recognize a glial water channel protein, Aquaporin-4 (AQP4) expressed as two major isoforms, M1- and M23-AQP4, in which the plasma membrane form orthogonal arrays of particles (OAPs). AQP4-M23 is the OAP-forming isoform, whereas AQP4-M1 alone is unable to form OAPs.

Background: Neuromyelitis optica (NMO) is an inflammatory disease associating optic neuritis and myelitis. Recently, several works showed that optical coherence tomography (OCT) should be an interesting method of disease severity.

The normal function of the urinary bladder is to store and expel urine in a coordinated, controlled fashion. This coordinated activity is regulated by the central and peripheral nervous systems.