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Posts tagged: neuromyelitis

Association of Neuromyelitis Optica With Severe and Intractable Pain. Qian P, Lancia S, Alvarez E, Klawiter EC, Cross AH, Naismith RT. Abstract OBJECTIVE To contrast differences in pain and treatment outcomes between neuromyelitis optica (NMO) and multiple sclerosis (MS)


Clinical Usefulness of Cell-based Indirect Immunofluorescence Assay for the Detection of Aquaporin-4 Antibodies in Neuromyelitis Optica Spectrum Disorder Eun-suk Kang, M.D.,1 Ju-Hong Min, M.D.,2 Kwang Ho Lee, M.D.,2 and Byoung Joon Kim, M.D.2 Author information ? Article notes ? Copyright and License information ? Go to: Abstract. Background The presence of antibodies to aquaporin-4 (AQP4) has been identified as a key characteristic of neuromyelitis optica spectrum disorder (NMOSD), an autoimmune inflammatory demyelinating central nervous system (CNS) disorder. We evaluated the performance of a cell-based indirect immunofluorescence assay (CIIFA) for detecting AQP4 antibodies using antigen prepared with a recombinant AQP4 peptide transfection technique and assessed the usefulness of CIIFA for diagnosis of NMOSD in routine clinical practice.


Original Article Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content, or supramolecular assembly Andrea Rossi1,2, Julien Ratelade1,2, Marios C. Papadopoulos3, Jeffrey L.


Neuromyelitis optica following thymectomy with severe spinal cord atrophy after frequent relapses for 30 years]. [Article in Japanese] Hironishi M, Ishimoto S, Sawanishi T, Miwa H, Kawachi I, Kondo T. Source Department of Internal Medicine, Seishokai Kasei-Tamura Hospital.


Diffuse and heterogeneous T2-hyperintense lesions in the splenium are characteristic of neuromyelitis optica.


Notable Increased Cerebrospinal Fluid Levels of Soluble Interleukin-6 Receptors in Neuromyelitis Optica. Wang H, Wang K, Zhong X, Dai Y, Qiu W, Wu A, Hu X.


Neuromyelitis optica.


Neuromyelitis optica in a patient with pemphigus foliaceus. Salazar R, Cerghet M, Farhat E, Lim HW


Abstract Neuromyelitis optica is an autoimmune disorder characterized by optic neuritis, transverse myelitis, and aquaporin-4 autoantibodies.


Keywords:Devic’s syndrome;neuromyelitis optica;plasma exchange;apheresis;steroid-refractory;MRI Abstract Neuromyelitis optica (NMO) is a severe inflammatory demyelinating disease of the central nervous system with exacerbations involving the optic nerves, spinal cord, or both. This study explores the utility of maintenance plasma exchange (mTPE) as a therapy in patients with relapsing, corticosteroid-refractory, NMO. This retrospective case series presents data on patients who were diagnosed with NMO using currently accepted criteria


Brain Lesions May Serve as Diagnostic Criteria for Neuromyelitis Optica 2011;19(8):13. A majority of patients with neuromyelitis optica also experience disease-specific brain lesions that could help distinguish neuromyelitis optica from multiple sclerosis. MONTREAL—Imaging studies of patients with neuromyelitis optica (NMO)–spectrum disorders reveal that effects of the aquaporin-4 (AQP4) autoantibody, a marker of the disease, may extend beyond the spinal cord and optic nerve, according to researchers


H.R. 4138 : Neuromyelitis Optica Consortium Act 112 th Congress: 2011-2012


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