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Posts tagged: nmosd

Source: Neurology Today Conference Reporter: ECTRIMS Congress PARIS—Should myelin oligodendrocyte glycoprotein (MOG) antibody disease, which causes brain inflammation, be no longer considered a disorder in the neuromyelitis optica…


J Neuroinflammation. 2016 Nov 1;13(1):282. Pache F1,2, Zimmermann H1,2, Mikolajczak J1, Schumacher S1, Lacheta A1, Oertel FC1, Bellmann-Strobl J1,3, Jarius S4, Wildemann B4, Reindl M5,…


J Neuroinflammation. 2016 Nov 1;13(1):281. Jarius S1, Kleiter I2, Ruprecht K3, Asgari N4, Pitarokoili K2, Borisow N5,6, Hümmert MW7, Trebst C7, Pache F5,6, Winkelmann A8,…


Aquaporin-4 Antibodies Are Not Related to HTLV-1 Associated Myelopathy.


Rinsho Shinkeigaku. 2012 Jan;52(1):19-24.


Azathioprine: Tolerability, efficacy, and predictors of benefit in neuromyelitis optica. Costanzi C , Matiello M , Lucchinetti CF , Weinshenker BG , Pittock SJ , Mandrekar J , Thapa P , McKeon A .


Multiple sclerosis: clinical aspects Sunday, May 29, 2011, 12:00 – 13:00 Neuromyelitis optica spectrum disorder: the importance of NMO-IgG in clinical practice M. Radaelli, V


Dujmovic I, Mader S, Schanda K, Deisenhammer F, Stojsavljevic N, Kostic J, Berger T, Drulovic J, Reindl M? Temporal dynamics of cerebrospinal fluid anti-aquaporin-4 antibodies in patients with neuromyelitis optica spectrum disorders. [JOURNAL ARTICLE] J Neuroimmunol 2011?Feb?10. Neuromyelitis optica spectrum disorders (NMOSD) are associated with anti-aquaporin-4 autoantibodies (AQP4-IgG).


AQP4 water channels are thought to be the target of autoimmune attack in neuromyelitis optica-spectrum disorders (NMOsd). AQP4 are highly expressed on ventricular ependyma.


Neuromyelitis optica spectrum disorders (NMOSD) are associated with anti-aquaporin-4 autoantibodies (AQP4-IgG). Limited data is available on longitudinal cerebrospinal fluid (CSF) AQP4-IgG and their relation to disease activity and inflammatory parameters. AQP4-IgG titers were measured in matched longitudinal serum and CSF samples of 12 patients with NMOSD by an immunofluorescence assay and correlated with clinical parameters


Objectives: the aim of our study was to investigate whether the presence of IgG-NMO antibody is associated with a different pattern of response at visual evoked potentials (VEPs) in patients affected by neuromyelites optica spectrum of disorders (NMOsd) with optic neuritis (ON). Methods: we retrospectively studied clinical, immunological and neurophysiological data from 28 patients affected by NMOsd who presented at least one optic neuritis (16 patients bilateral and 12 unilateral).