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Posts tagged: optica

Association of Neuromyelitis Optica With Severe and Intractable Pain. Qian P, Lancia S, Alvarez E, Klawiter EC, Cross AH, Naismith RT. Abstract OBJECTIVE To contrast differences in pain and treatment outcomes between neuromyelitis optica (NMO) and multiple sclerosis (MS)


Clinical Usefulness of Cell-based Indirect Immunofluorescence Assay for the Detection of Aquaporin-4 Antibodies in Neuromyelitis Optica Spectrum Disorder Eun-suk Kang, M.D.,1 Ju-Hong Min, M.D.,2 Kwang Ho Lee, M.D.,2 and Byoung Joon Kim, M.D.2 Author information ? Article notes ? Copyright and License information ? Go to: Abstract. Background The presence of antibodies to aquaporin-4 (AQP4) has been identified as a key characteristic of neuromyelitis optica spectrum disorder (NMOSD), an autoimmune inflammatory demyelinating central nervous system (CNS) disorder. We evaluated the performance of a cell-based indirect immunofluorescence assay (CIIFA) for detecting AQP4 antibodies using antigen prepared with a recombinant AQP4 peptide transfection technique and assessed the usefulness of CIIFA for diagnosis of NMOSD in routine clinical practice.


Human Umbilical Cord Mesenchymal Stem Cell Therapy on Neuromyelitis Optica. Lu Z, Ye D, Qian L, Wu J, Zhu L, Shao Y, Liu Z, Zhang X, Wang Z, Xu Y


Neuromyelitis optica following thymectomy with severe spinal cord atrophy after frequent relapses for 30 years]. [Article in Japanese] Hironishi M, Ishimoto S, Sawanishi T, Miwa H, Kawachi I, Kondo T. Source Department of Internal Medicine, Seishokai Kasei-Tamura Hospital.


Diffuse and heterogeneous T2-hyperintense lesions in the splenium are characteristic of neuromyelitis optica.


Notable Increased Cerebrospinal Fluid Levels of Soluble Interleukin-6 Receptors in Neuromyelitis Optica. Wang H, Wang K, Zhong X, Dai Y, Qiu W, Wu A, Hu X.


J Child Neurol. 2012 Jul 25.


Neuromyelitis optica.


Neuromyelitis optica in a patient with pemphigus foliaceus. Salazar R, Cerghet M, Farhat E, Lim HW


Keywords:Devic’s syndrome;neuromyelitis optica;plasma exchange;apheresis;steroid-refractory;MRI Abstract Neuromyelitis optica (NMO) is a severe inflammatory demyelinating disease of the central nervous system with exacerbations involving the optic nerves, spinal cord, or both. This study explores the utility of maintenance plasma exchange (mTPE) as a therapy in patients with relapsing, corticosteroid-refractory, NMO. This retrospective case series presents data on patients who were diagnosed with NMO using currently accepted criteria


H.R. 4138 : Neuromyelitis Optica Consortium Act 112 th Congress: 2011-2012


Cerebrospinal fluid B-cell expansion in longitudinally extensive transverse myelitis associated with neuromyelitis optica immunoglobulin G. Dale RC, Tantsis E, Merheb V, Brilot F. Source Neuroimmunology Group, Institute of Neuroscience and Muscle Research, The Children’s Hospital at Westmead, University of Sydney, Sydney, NSW, Australia


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