Posts tagged: population

The prevalence of neuromyelitis optica in South East Wales.

A population-based study of neuromyelitis optica in Caucasians N.

INTRODUCTION: The existence of antibodies to aquaporin-4 (AQP-4-ab) has identified neuromyelitis optica (NMO) and multiple sclerosis (MS) as different diseases. Although HLA-DRB1 alleles contribute to MS risk, recent studies suggest that HLA back-ground differs between patients with NMO or MS in non-Caucasians populations

Introduction: The association between susceptibility to MS and class II alleles of the major histocompatibility complex (MHC) is well established in MS patients but not in NMOR. The ethnicity has an important role in MS HLA DQ and DR profile. Brazilian population has ethnic particularities with a high mixed African and Caucasian Mediterranean population

Background: Despite similarities, neuromyelitis optica (NMO) can be distinguished from multiple sclerosis (MS) by clinical, radiological and serological findings.

Background: Myasthenia gravis (MG) and neuromyelitis optica (NMO, also known as Devic disease) are rare autoimmune disorders, with upper-limit prevalence estimates in the general population of 15 per 100 000 and 5 per 100 000, respectively. To our knowledge, an association between these diseases has not been previously reported.

Neuromyelitis optica is a central nervous system disease characterized by optic neuritis and transverse myelitis. It is a devastating illness, and early treatment may prevent future relapses and severe disability. However, there is much variability in protocols used for treatment.

Background: Neuromyelitis optica (NMO) is an inflammatory idiopathic and usually relapsing disease of the central nervous system, with a characteristic predilection for the optic nerves and spinal cord. MS exhibits a higher prevalence in Caucasian populations, whereas NMO is relatively more frequent in non-Caucasian individuals – Asians, Hispanics and Africans. Brazilian population represents interethnic crossings between people from America, Africa and Europe.