Published on April 2, 2010
Lawrence Steinman, MD – Stanford University:
NMO is a rugged disease. The experiences in the clinic done by skilled medical scientists are showing us what the triggers are for NMO, what the possible drugs are that will cure the disease, and how we might eventually improve function after we stopp the disease in its tracks.
Since the discovery of the APQ-4 antibody in 2004 the spectrum of NMO has dramatically changed and evolved to what we now consider NMOSD.
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The short answer is yes. The long answer is we don't know how that happens...after a patient relapses and we suppress the inflammation
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Spinal cord damage occurs in all patients with NMO, because it's one of the essential diagnostic criteria for NMO.
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In NMO, the immune system is too active, so all of our treatments are really directed at decreasing the immune system.
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