Brain lesions are not uncommon in neuromyelitis optica (NMO) patients with anti-aquaporin-4 (AQP4) antibody; however, the appearance of these lesions is said to be different from that of those in…
Consequences of NMO-IgG binding to aquaporin-4 in neuromyelitis optica. Hinson et al. (1) suggested a unique mechanism for the pathogenesis of neuromyelitis optica (NMO), a neuroinflammatory disease caused by binding…
Devic’s neuromyelitis optica is an inflammatory demyelinating disorder normally restricted to the optic nerves and spinal cord. Since the identification of a specific autoantibody directed against aquaporin 4, neuromyelitis optica-immunoglobulin…
April 26, 2018 — Vatican City — Victoria Jackson, Founder of The Guthy-Jackson Charitable Foundation (GJCF), was honored with the 2018 Pontifical Key Advocacy Award at Unite To Cure: Fourth…
Brain Lesions May Serve as Diagnostic Criteria for Neuromyelitis Optica 2011;19(8):13. A majority of patients with neuromyelitis optica also experience disease-specific brain lesions that could help distinguish neuromyelitis optica from…
J Neuroinflammation. 2016 Sep 26;13(1):279. Abstract BACKGROUND: Antibodies to myelin oligodendrocyte glycoprotein (MOG-IgG) have been suggested to play a role in a subset of patients with neuromyelitis optica and…
JAMA Neurol. 2017 Nov 13. doi: 10.1001/jamaneurol.2017.3196. Hamid SHM1, Whittam D1, Saviour M2, Alorainy A3, Mutch K1, Linaker S1, Solomon T4, Bhojak M1, Woodhall M5, Waters P5, Appleton R6, Duddy…
Autonomic Dysreflexia & Hyperreflexia Autonomic Dysreflexia Sections Autonomic Dysreflexia Mechanism of Autonomic Dysreflexia Causes of Autonomic Dysreflexia Functional Electrical Stimulation Headaches Autonomic Dysreflexia ? Autonomic Dysreflexia, also known as Hyperreflexia,…
Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system associated with autoantibodies against the glial water channel protein aquaporin-4. It has recently been reported that immunoglobulin from…
Utility and safety of rituximab in pediatric autoimmune and inflamm… – PubMed – NCBI. Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease. Dale RC 1, Brilot…
Alexander City, AL – In June 2016, the University of Alabama at Birmingham’s (UAB) Center for Pediatric Onset Demyelinating Disease (CPODD) hosted its annual retreat for families who have children…
What is #GivingTuesday? Entering its fifth year, #GivingTuesday is a global day of giving fueled by the power of social media and collaboration. Celebrated on the Tuesday following Thanksgiving (in…